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Oncogenic MYC amplifies mitotic perturbations

The oncogenic transcription factor MYC modulates vast arrays of genes, thereby influencing numerous biological pathways including biogenesis, metabolism, proliferation, apoptosis and pluripotency. When deregulated, MYC drives genomic instability via several mechanisms including aberrant proliferatio...

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Detalles Bibliográficos
Autores principales: Littler, Samantha, Sloss, Olivia, Geary, Bethany, Pierce, Andrew, Whetton, Anthony D., Taylor, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731591/
https://www.ncbi.nlm.nih.gov/pubmed/31455158
http://dx.doi.org/10.1098/rsob.190136