Cargando…
Oncogenic MYC amplifies mitotic perturbations
The oncogenic transcription factor MYC modulates vast arrays of genes, thereby influencing numerous biological pathways including biogenesis, metabolism, proliferation, apoptosis and pluripotency. When deregulated, MYC drives genomic instability via several mechanisms including aberrant proliferatio...
Autores principales: | Littler, Samantha, Sloss, Olivia, Geary, Bethany, Pierce, Andrew, Whetton, Anthony D., Taylor, Stephen S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731591/ https://www.ncbi.nlm.nih.gov/pubmed/31455158 http://dx.doi.org/10.1098/rsob.190136 |
Ejemplares similares
-
MYC Is a Major Determinant of Mitotic Cell Fate
por: Topham, Caroline, et al.
Publicado: (2015) -
Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers
por: Bennett, Ailsa, et al.
Publicado: (2016) -
Mcl-1 dynamics influence mitotic slippage and death in mitosis
por: Sloss, Olivia, et al.
Publicado: (2016) -
AMPLIFIED ALLELE OF THE HUMAN N‐myc ONCOGENE IN NEUROBLASTOMAS
por: Yamada, Masao, et al.
Publicado: (1988) -
In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential
por: Raffeiner, Philipp, et al.
Publicado: (2014)