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Histone deacetylase 1 suppresses Krüppel homolog 1 gene expression and influences juvenile hormone action in Tribolium castaneum

Posttranslational modifications, including acetylation and deacetylation of histones and other proteins, modulate hormone action. In Tribolium castaneum TcA cells, Trichostatin A, a histone deacetylase (HDAC) inhibitor, mimics juvenile hormone (JH) in inducing JH response genes (e.g., Kr-h1), sugges...

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Detalles Bibliográficos
Autores principales: George, Smitha, Gaddelapati, Sharath Chandra, Palli, Subba Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731676/
https://www.ncbi.nlm.nih.gov/pubmed/31439816
http://dx.doi.org/10.1073/pnas.1909554116