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Role of soluble endoglin in BMP9 signaling

Endoglin (ENG) is a coreceptor of the transforming growth factor-β (TGFβ) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. Its extracellular domain can be cleaved and released into the circulation as soluble ENG (sENG). High circulating l...

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Detalles Bibliográficos
Autores principales: Lawera, Aleksandra, Tong, Zhen, Thorikay, Midory, Redgrave, Rachael E., Cai, Jie, van Dinther, Maarten, Morrell, Nicholas W., Afink, Gijs B., Charnock-Jones, D. Stephen, Arthur, Helen M., ten Dijke, Peter, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731690/
https://www.ncbi.nlm.nih.gov/pubmed/31431534
http://dx.doi.org/10.1073/pnas.1816661116