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Proteomic method to extract, concentrate, digest and enrich peptides from fossils with coloured (humic) substances for mass spectrometry analyses

Humic substances are breakdown products of decaying organic matter that co-extract with proteins from fossils. These substances are difficult to separate from proteins in solution and interfere with analyses of fossil proteomes. We introduce a method combining multiple recent advances in extraction...

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Detalles Bibliográficos
Autores principales: Schroeter, Elena R., Blackburn, Kevin, Goshe, Michael B., Schweitzer, Mary H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731700/
https://www.ncbi.nlm.nih.gov/pubmed/31598217
http://dx.doi.org/10.1098/rsos.181433