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MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression
OBJECTIVES: Osteosarcoma (OS) is the most common bone cancer diagnosed in children and adolescents. Expression of APE1 is commonly increased in OS, and this is negatively correlated with a sensitivity to platinum and a favorable prognosis. However, the mechanism underlying high APE1 expression in OS...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731985/ https://www.ncbi.nlm.nih.gov/pubmed/31564904 http://dx.doi.org/10.2147/OTT.S194800 |