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Evolutionary history of disease‐susceptibility loci identified in longitudinal exome‐wide association studies

BACKGROUND: Our longitudinal exome‐wide association studies previously detected various genetic determinants of complex disorders using ~26,000 single‐nucleotide polymorphisms (SNPs) that passed quality control and longitudinal medical examination data (mean follow‐up period, 5 years) in 4884–6022 J...

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Detalles Bibliográficos
Autores principales: Yasukochi, Yoshiki, Sakuma, Jun, Takeuchi, Ichiro, Kato, Kimihiko, Oguri, Mitsutoshi, Fujimaki, Tetsuo, Horibe, Hideki, Yamada, Yoshiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732299/
https://www.ncbi.nlm.nih.gov/pubmed/31402603
http://dx.doi.org/10.1002/mgg3.925