Identification of key candidate targets and pathways for the targeted treatment of leukemia stem cells of chronic myelogenous leukemia using bioinformatics analysis

BACKGROUND: Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm that arises from the acquisition of constitutively active BCR‐ABL tyrosine kinase in hematopoietic stem cells. The persistence of bone marrow leukemia stem cells (LSCs) is the main cause of TKI resistance and CML relapse...

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Detalles Bibliográficos
Autores principales: Li, Huayao, Liu, Lijuan, Zhuang, Jing, Liu, Cun, Zhou, Chao, Yang, Jing, Gao, Chundi, Liu, Gongxi, Sun, Changgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732304/
https://www.ncbi.nlm.nih.gov/pubmed/31373443
http://dx.doi.org/10.1002/mgg3.851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732304/
https://www.ncbi.nlm.nih.gov/pubmed/31373443
http://dx.doi.org/10.1002/mgg3.851

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