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Whole‐exome sequencing and immunohistochemistry findings in von Hippel–Lindau disease
BACKGROUND: von Hippel–Lindau (VHL) disease has a hereditary, autosomal dominant pattern, and multiple tumors can develop in multiple organs of a single patient. However, the exact mechanisms of tumorigenesis are unclear, and further studies are needed to clarify whether the same signaling pathways...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732316/ https://www.ncbi.nlm.nih.gov/pubmed/31317677 http://dx.doi.org/10.1002/mgg3.880 |