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HPO-Shuffle: an associated gene prioritization strategy and its application in drug repurposing for the treatment of canine epilepsy

Epilepsy is a common neurological disorder that affects mammalian species including human beings and dogs. In order to discover novel drugs for the treatment of canine epilepsy, multiomics data were analyzed to identify epilepsy associated genes. In this research, the original ranking of associated...

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Detalles Bibliográficos
Autores principales: Wang, Shuguang, Meng, Xiangyu, Wang, Yuxing, Liu, Yemao, Xia, Jingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732366/
https://www.ncbi.nlm.nih.gov/pubmed/31427480
http://dx.doi.org/10.1042/BSR20191247