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Fbxw7 and Skp2 Regulate Stem Cell Switch between Quiescence and Mitotic Division in Lung Adenocarcinoma

BACKGROUND/AIMS: The molecular mechanism of dormancy initiation of cancer stem cells (CSCs) is not clear. This study was to explore the molecular mechanism by which CSCs switch from mitotic division to quiescence. METHODS: MTT assays, flow cytometry, Western blotting, qRT-PCR, and immunofluorescence...

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Detalles Bibliográficos
Autores principales: Zhang, Wenzhu, Ren, Zihan, Jia, Lanling, Li, Xin, Jia, Xinshan, Han, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732578/
https://www.ncbi.nlm.nih.gov/pubmed/31534970
http://dx.doi.org/10.1155/2019/9648269