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Modular pathway engineering of key precursor supply pathways for lacto-N-neotetraose production in Bacillus subtilis

BACKGROUND: Lacto-N-neotetraose (LNnT) is one of the important ingredients of human milk oligosaccharides, which can enhance immunity, regulate intestinal bacteria and promote cell maturation. RESULTS: In this study, the synthetic pathway of LNnT was constructed by co-expressing the lactose permease...

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Detalles Bibliográficos
Autores principales: Dong, Xiaomin, Li, Nan, Liu, Zhenmin, Lv, Xueqin, Li, Jianghua, Du, Guocheng, Wang, Miao, Liu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732834/
https://www.ncbi.nlm.nih.gov/pubmed/31516551
http://dx.doi.org/10.1186/s13068-019-1551-3