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Association between SFRP promoter hypermethylation and different types of cancer: A systematic review and meta-analysis

Abnormal methylation of secreted frizzled-related proteins (SFRPs) has been observed in various human cancer types. The loss of SFRP gene expression induces the activation of the Wnt pathway and is a vital mechanism for tumorigenesis and development. The aim of the present systematic review was to a...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Xie, Yang, Li, Mengying, Zhou, Fenfang, Zhong, Zhenyang, Liu, Yuting, Wang, Feng, Qi, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733008/
https://www.ncbi.nlm.nih.gov/pubmed/31516566
http://dx.doi.org/10.3892/ol.2019.10709