EXT1, Regulated by MiR-665, Promotes Cell Apoptosis via ERK1/2 Signaling Pathway in Acute Lymphoblastic Leukemia

BACKGROUND: EXT1 is an endoplasmic reticulum-resident glycosyl transferase whose intracellular expression alters the biosynthesis and distribution of heparan sulfate. EXT1 is regarded as a classic tumor suppressor. MiR-665 can act as either an oncogene or tumor-suppressing gene in different tumors....

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Detalles Bibliográficos
Autores principales: Liu, Na-wei, Huang, Xin, Liu, Shuang, Lu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733154/
https://www.ncbi.nlm.nih.gov/pubmed/31465316
http://dx.doi.org/10.12659/MSM.918295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733154/
https://www.ncbi.nlm.nih.gov/pubmed/31465316
http://dx.doi.org/10.12659/MSM.918295

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