Toward the establishment of a standardized pre-clinical porcine model to predict food effects – Case studies on fenofibrate and paracetamol

A preclinical porcine model that reliably predicts human food effect of fenofibrate was developed. Fenofibrate was administered to pigs as model compound with a positive food effect. Two different types of fed conditions were explored: a FDA style breakfast and a standard pig pellet feed. In order t...

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Detalles Bibliográficos
Autores principales: Henze, Laura J., Koehl, Niklas J., O'Shea, Joseph P., Holm, René, Vertzoni, Maria, Griffin, Brendan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733283/
https://www.ncbi.nlm.nih.gov/pubmed/31517282
http://dx.doi.org/10.1016/j.ijpx.2019.100017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733283/
https://www.ncbi.nlm.nih.gov/pubmed/31517282
http://dx.doi.org/10.1016/j.ijpx.2019.100017

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