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Biophysical model to predict lung delivery from a dual bronchodilator dry-powder inhaler
A biophysical lung model was designed to predict inhaled drug deposition in patients with obstructive airway disease, and quantitatively investigate sources of deposition variability. Different mouth-throat anatomies at varying simulated inhalation flows were used to calculate the lung dose of indac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733285/ https://www.ncbi.nlm.nih.gov/pubmed/31517283 http://dx.doi.org/10.1016/j.ijpx.2019.100018 |