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Biophysical model to predict lung delivery from a dual bronchodilator dry-powder inhaler

A biophysical lung model was designed to predict inhaled drug deposition in patients with obstructive airway disease, and quantitatively investigate sources of deposition variability. Different mouth-throat anatomies at varying simulated inhalation flows were used to calculate the lung dose of indac...

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Detalles Bibliográficos
Autores principales: Dolovich, Myrna B., Kuttler, Andreas, Dimke, Thomas J., Usmani, Omar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733285/
https://www.ncbi.nlm.nih.gov/pubmed/31517283
http://dx.doi.org/10.1016/j.ijpx.2019.100018