Impact of drug loading in mesoporous silica-amorphous formulations on the physical stability of drugs with high recrystallization tendency

In this study, a method is described to determine the monolayer loading capacity (MLC) of the drugs naproxen and ibuprofen, both having high recrystallization tendencies, in mesoporous silica (MS), a well known carrier that is able to stabilize the amorphous form of a drug. The stabilization has bee...

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Detalles Bibliográficos
Autores principales: Antonino, Rayane S.C.M.Q., Ruggiero, Michael, Song, Zihui, Nascimento, Thais Leite, Lima, Eliana Martins, Bohr, Adam, Knopp, Matthias Manne, Löbmann, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733286/
https://www.ncbi.nlm.nih.gov/pubmed/31517291
http://dx.doi.org/10.1016/j.ijpx.2019.100026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733286/
https://www.ncbi.nlm.nih.gov/pubmed/31517291
http://dx.doi.org/10.1016/j.ijpx.2019.100026

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