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Impact of drug loading in mesoporous silica-amorphous formulations on the physical stability of drugs with high recrystallization tendency
In this study, a method is described to determine the monolayer loading capacity (MLC) of the drugs naproxen and ibuprofen, both having high recrystallization tendencies, in mesoporous silica (MS), a well known carrier that is able to stabilize the amorphous form of a drug. The stabilization has bee...
Autores principales: | Antonino, Rayane S.C.M.Q., Ruggiero, Michael, Song, Zihui, Nascimento, Thais Leite, Lima, Eliana Martins, Bohr, Adam, Knopp, Matthias Manne, Löbmann, Korbinian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733286/ https://www.ncbi.nlm.nih.gov/pubmed/31517291 http://dx.doi.org/10.1016/j.ijpx.2019.100026 |
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