Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures

The efficient and reproducible production of nanoparticles using bulk nanoprecipitation methods is still challenging because of low batch to batch reproducibility. Here, we optimize a bulk nanoprecipitation method using design of experiments and translate to a microfluidic device to formulate surfac...

Descripción completa

Detalles Bibliográficos
Autores principales: Streck, Sarah, Neumann, Henriette, Nielsen, Hanne Mørck, Rades, Thomas, McDowell, Arlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733288/
https://www.ncbi.nlm.nih.gov/pubmed/31517295
http://dx.doi.org/10.1016/j.ijpx.2019.100030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733288/
https://www.ncbi.nlm.nih.gov/pubmed/31517295
http://dx.doi.org/10.1016/j.ijpx.2019.100030

Ejemplares similares