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Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures

The efficient and reproducible production of nanoparticles using bulk nanoprecipitation methods is still challenging because of low batch to batch reproducibility. Here, we optimize a bulk nanoprecipitation method using design of experiments and translate to a microfluidic device to formulate surfac...

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Detalles Bibliográficos
Autores principales:	Streck, Sarah, Neumann, Henriette, Nielsen, Hanne Mørck, Rades, Thomas, McDowell, Arlene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733288/ https://www.ncbi.nlm.nih.gov/pubmed/31517295 http://dx.doi.org/10.1016/j.ijpx.2019.100030

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