Using zeta potential to study the ionisation behaviour of polymers employed in modified-release dosage forms and estimating their pK(a)

A range of enteric polymers is used in pharmaceutical industry for developing gastro-resistant formulations. It is generally implied that these coatings are interchangeable due to similar dissolution pH thresholds reported by suppliers. Despite rapid dissolution in compendial phosphate buffers, thes...

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Detalles Bibliográficos
Autores principales: Barbosa, Joao A.C., Abdelsadig, Malaz S.E., Conway, Barbara R., Merchant, Hamid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733289/
https://www.ncbi.nlm.nih.gov/pubmed/31517289
http://dx.doi.org/10.1016/j.ijpx.2019.100024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733289/
https://www.ncbi.nlm.nih.gov/pubmed/31517289
http://dx.doi.org/10.1016/j.ijpx.2019.100024

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