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Using zeta potential to study the ionisation behaviour of polymers employed in modified-release dosage forms and estimating their pK(a)
A range of enteric polymers is used in pharmaceutical industry for developing gastro-resistant formulations. It is generally implied that these coatings are interchangeable due to similar dissolution pH thresholds reported by suppliers. Despite rapid dissolution in compendial phosphate buffers, thes...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733289/ https://www.ncbi.nlm.nih.gov/pubmed/31517289 http://dx.doi.org/10.1016/j.ijpx.2019.100024 |