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Impact of electroviscous effect on viscosity in developing highly concentrated protein formulations: Lessons from non-protein charged colloids

Subcutaneous delivery of highly concentrated protein formulations is paramount for reducing healthcare cost and improving patient compliance, where reducing the solution viscosity of formulations is critical for drug delivery. The objective of this paper is to provide some mechanistic understanding...

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Detalles Bibliográficos
Autores principales: Li, Jinjiang, Cheng, Yuan, Chen, Xiaodong, Zheng, Songyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733305/
https://www.ncbi.nlm.nih.gov/pubmed/31545855
http://dx.doi.org/10.1016/j.ijpx.2018.100002