Industrial application of heat- and mass balance model for fluid-bed granulation for technology transfer and design space exploration

This work demonstrates the application of state-of-the-art modeling techniques in pharmaceutical manufacturing for fluid bed granulation at varying scales to successfully predict process conditions and ultimately replace experiments during a technology transfer of five products. We describe a mathem...

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Detalles Bibliográficos
Autores principales: Ochsenbein, David R., Billups, Matthew, Hong, Bingbing, Schäfer, Elisabeth, Marchut, Alexander J., Lyngberg, Olav K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733368/
https://www.ncbi.nlm.nih.gov/pubmed/31517293
http://dx.doi.org/10.1016/j.ijpx.2019.100028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733368/
https://www.ncbi.nlm.nih.gov/pubmed/31517293
http://dx.doi.org/10.1016/j.ijpx.2019.100028

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