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Designing combination therapies with modeling chaperoned machine learning

Chemotherapy resistance is a major challenge to the effective treatment of cancer. Thus, a systematic pipeline for the efficient identification of effective combination treatments could bring huge biomedical benefit. In order to facilitate rational design of combination therapies, we developed a com...

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Detalles Bibliográficos
Autores principales: Zhang, Yin, Huynh, Julie M., Liu, Guan-Sheng, Ballweg, Richard, Aryeh, Kayenat S., Paek, Andrew L., Zhang, Tongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733436/
https://www.ncbi.nlm.nih.gov/pubmed/31498788
http://dx.doi.org/10.1371/journal.pcbi.1007158