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The wing of the ToxR winged helix-turn-helix domain is required for DNA binding and activation of toxT and ompU
ToxR and TcpP, two winged helix-turn-helix (w-HTH) family transcription factors, co-activate expression of the toxT promoter in Vibrio cholerae. ToxT then directly regulates a number of genes required for virulence. In addition to co-activation of toxT, ToxR can directly activate the ompU promoter a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733452/ https://www.ncbi.nlm.nih.gov/pubmed/31498842 http://dx.doi.org/10.1371/journal.pone.0221936 |