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The wing of the ToxR winged helix-turn-helix domain is required for DNA binding and activation of toxT and ompU

ToxR and TcpP, two winged helix-turn-helix (w-HTH) family transcription factors, co-activate expression of the toxT promoter in Vibrio cholerae. ToxT then directly regulates a number of genes required for virulence. In addition to co-activation of toxT, ToxR can directly activate the ompU promoter a...

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Detalles Bibliográficos
Autores principales: Morgan, Sarah J., French, Emily L., Plecha, Sarah C., Krukonis, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733452/
https://www.ncbi.nlm.nih.gov/pubmed/31498842
http://dx.doi.org/10.1371/journal.pone.0221936