Glucocorticoid stimulation increases cardiac contractility by SGK1-dependent SOCE-activation in rat cardiac myocytes

AIMS: Glucocorticoid (GC) stimulation has been shown to increase cardiac contractility by elevated intracellular [Ca] but the sources for Ca entry are unclear. This study aims to determine the role of store-operated Ca entry (SOCE) for GC-mediated inotropy. METHODS AND RESULTS: Dexamethasone (Dex) p...

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Detalles Bibliográficos
Autores principales: Wester, Michael, Heller, Anton, Gruber, Michael, Maier, Lars S., Schach, Christian, Wagner, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733454/
https://www.ncbi.nlm.nih.gov/pubmed/31498847
http://dx.doi.org/10.1371/journal.pone.0222341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733454/
https://www.ncbi.nlm.nih.gov/pubmed/31498847
http://dx.doi.org/10.1371/journal.pone.0222341

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