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IFN-γ restores the impaired function of RNase L and induces mitochondria-mediated apoptosis in lung cancer

RNase L is an essential component in interferon (IFN)-mediated antiviral signaling that showed antitumor effects in cancer. Cancer immunotherapy based on interferon has achieved encouraging results that indicate an applicable potential for cancer therapy. Here we showed that function of RNase L, tho...

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Detalles Bibliográficos
Autores principales: Yin, Huijing, Jiang, Zhengyu, Wang, Shuoer, Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733796/
https://www.ncbi.nlm.nih.gov/pubmed/31501431
http://dx.doi.org/10.1038/s41419-019-1902-9