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IFN-γ restores the impaired function of RNase L and induces mitochondria-mediated apoptosis in lung cancer
RNase L is an essential component in interferon (IFN)-mediated antiviral signaling that showed antitumor effects in cancer. Cancer immunotherapy based on interferon has achieved encouraging results that indicate an applicable potential for cancer therapy. Here we showed that function of RNase L, tho...
Autores principales: | Yin, Huijing, Jiang, Zhengyu, Wang, Shuoer, Zhang, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733796/ https://www.ncbi.nlm.nih.gov/pubmed/31501431 http://dx.doi.org/10.1038/s41419-019-1902-9 |
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