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The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood

Dysregulation of splicing factor expression is emerging as a driver of human ageing; levels of transcripts encoding splicing regulators have previously been implicated in ageing and cellular senescence both in vitro and in vivo. We measured the expression levels of an a priori panel of 20 age- or se...

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Detalles Bibliográficos
Autores principales: Lee, Benjamin P., Pilling, Luke C., Bandinelli, Stefania, Ferrucci, Luigi, Melzer, David, Harries, Lorna W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819/
https://www.ncbi.nlm.nih.gov/pubmed/31292793
http://dx.doi.org/10.1007/s10522-019-09819-0