G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10

The aberrant accumulation of ubiquitinated protein aggregates in cells plays a critical role in the pathogenesis of several degenerative diseases, including Parkinson disease (PD) and cystic fibrosis (CF). In this study, we found that Ras GTPase-activating protein-binding protein 1 (G3BP1) inhibits...

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Detalles Bibliográficos
Autores principales: Anisimov, Sergei, Takahashi, Masahiko, Kakihana, Taichi, Katsuragi, Yoshinori, Kitaura, Hiroki, Zhang, Lu, Kakita, Akiyoshi, Fujii, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733845/
https://www.ncbi.nlm.nih.gov/pubmed/31501480
http://dx.doi.org/10.1038/s41598-019-46237-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733845/
https://www.ncbi.nlm.nih.gov/pubmed/31501480
http://dx.doi.org/10.1038/s41598-019-46237-1

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