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G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10
The aberrant accumulation of ubiquitinated protein aggregates in cells plays a critical role in the pathogenesis of several degenerative diseases, including Parkinson disease (PD) and cystic fibrosis (CF). In this study, we found that Ras GTPase-activating protein-binding protein 1 (G3BP1) inhibits...
Autores principales: | Anisimov, Sergei, Takahashi, Masahiko, Kakihana, Taichi, Katsuragi, Yoshinori, Kitaura, Hiroki, Zhang, Lu, Kakita, Akiyoshi, Fujii, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733845/ https://www.ncbi.nlm.nih.gov/pubmed/31501480 http://dx.doi.org/10.1038/s41598-019-46237-1 |
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