Mosaicism of XX and XXY cells accounts for high copy number of Toll like Receptor 7 and8 genes in peripheral blood of men with Rheumatoid Arthritis

The X chromosome, hemizygous in males, contains numerous genes important to immunological and hormonal function. Alterations in X-linked gene dosage are suspected to contribute to female predominance in autoimmunity. A powerful example of X-linked dosage involvement comes from the BXSB murine lupus...

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Detalles Bibliográficos
Autores principales: Martin, Gabriel V., Kanaan, Sami B., Hemon, Marie F., Azzouz, Doua F., El Haddad, Marina, Balandraud, Nathalie, Mignon-Ravix, Cécile, Picard, Christophe, Arnoux, Fanny, Martin, Marielle, Roudier, Jean, Auger, Isabelle, Lambert, Nathalie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733859/
https://www.ncbi.nlm.nih.gov/pubmed/31501466
http://dx.doi.org/10.1038/s41598-019-49309-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733859/
https://www.ncbi.nlm.nih.gov/pubmed/31501466
http://dx.doi.org/10.1038/s41598-019-49309-4

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