Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation

Anesthetics are generally associated with sedation, but some anesthetics can also increase brain and motor activity—a phenomenon known as paradoxical excitation. Previous studies have identified GABA(A) receptors as the primary targets of most anesthetic drugs, but how these compounds produce parado...

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Detalles Bibliográficos
Autores principales: McCarroll, Matthew N., Gendelev, Leo, Kinser, Reid, Taylor, Jack, Bruni, Giancarlo, Myers-Turnbull, Douglas, Helsell, Cole, Carbajal, Amanda, Rinaldi, Capria, Kang, Hye Jin, Gong, Jung Ho, Sello, Jason K., Tomita, Susumu, Peterson, Randall T., Keiser, Michael J., Kokel, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733874/
https://www.ncbi.nlm.nih.gov/pubmed/31501447
http://dx.doi.org/10.1038/s41467-019-11936-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733874/
https://www.ncbi.nlm.nih.gov/pubmed/31501447
http://dx.doi.org/10.1038/s41467-019-11936-w

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