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Combinatorial Effect of ARTP Mutagenesis and Ribosome Engineering on an Industrial Strain of Streptomyces albus S12 for Enhanced Biosynthesis of Salinomycin

Salinomycin, an important polyketide, has been widely utilized in agriculture to inhibit growth of pathogenic bacteria. In addition, salinomycin has great potential in treatment of cancer cells. Due to inherited characteristics and beneficial potential, its demand is also inclining. Therefore, there...

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Detalles Bibliográficos
Autores principales: Zhang, Kuipu, Mohsin, Ali, Dai, Yichen, Chen, Zhongbing, Zhuang, Yingping, Chu, Ju, Guo, Meijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733881/
https://www.ncbi.nlm.nih.gov/pubmed/31552238
http://dx.doi.org/10.3389/fbioe.2019.00212