Robust and interpretable PAM50 reclassification exhibits survival advantage for myoepithelial and immune phenotypes

We introduce a classification of breast tumors into seven classes which are more clearly defined by interpretable mRNA signatures along the PAM50 gene set than the five traditional PAM50 intrinsic subtypes. Each intrinsic subtype is partially concordant with one of our classes, and the two additiona...

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Detalles Bibliográficos
Autores principales: Mathews, James C., Nadeem, Saad, Levine, Arnold J., Pouryahya, Maryam, Deasy, Joseph O., Tannenbaum, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733897/
https://www.ncbi.nlm.nih.gov/pubmed/31531391
http://dx.doi.org/10.1038/s41523-019-0124-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733897/
https://www.ncbi.nlm.nih.gov/pubmed/31531391
http://dx.doi.org/10.1038/s41523-019-0124-8

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