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Robust and interpretable PAM50 reclassification exhibits survival advantage for myoepithelial and immune phenotypes
We introduce a classification of breast tumors into seven classes which are more clearly defined by interpretable mRNA signatures along the PAM50 gene set than the five traditional PAM50 intrinsic subtypes. Each intrinsic subtype is partially concordant with one of our classes, and the two additiona...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733897/ https://www.ncbi.nlm.nih.gov/pubmed/31531391 http://dx.doi.org/10.1038/s41523-019-0124-8 |