Cargando…

Moving Mountains—The BRCA1 Promotion of DNA Resection

DNA double-strand breaks (DSBs) occur in our cells in the context of chromatin. This type of lesion is toxic, entirely preventing genome continuity and causing cell death or terminal arrest. Several repair mechanisms can act on DNA surrounding a DSB, only some of which carry a low risk of mutation,...

Descripción completa

Detalles Bibliográficos
Autores principales: Densham, Ruth M., Morris, Joanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733915/
https://www.ncbi.nlm.nih.gov/pubmed/31552267
http://dx.doi.org/10.3389/fmolb.2019.00079