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A positive feedback loop of β-catenin/CCR2 axis promotes regorafenib resistance in colorectal cancer
Resistance to molecular targeted therapies is a significant challenge for advanced colorectal cancer (CRC). Understanding the underlying mechanisms and developing effective strategies against regorafenib resistance are highly desired in the clinic. Here, we screened the expression of chemokine recep...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733926/ https://www.ncbi.nlm.nih.gov/pubmed/31501414 http://dx.doi.org/10.1038/s41419-019-1906-5 |