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A positive feedback loop of β-catenin/CCR2 axis promotes regorafenib resistance in colorectal cancer

Resistance to molecular targeted therapies is a significant challenge for advanced colorectal cancer (CRC). Understanding the underlying mechanisms and developing effective strategies against regorafenib resistance are highly desired in the clinic. Here, we screened the expression of chemokine recep...

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Detalles Bibliográficos
Autores principales: Ou, Baochi, Cheng, Xi, Xu, Zhuoqing, Chen, Chun, Shen, Xiaohui, Zhao, Jingkun, Lu, Aiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733926/
https://www.ncbi.nlm.nih.gov/pubmed/31501414
http://dx.doi.org/10.1038/s41419-019-1906-5