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Unveiling the multi-step solubilization mechanism of sub-micron size vesicles by detergents

The solubilization of membranes by detergents is critical for many technological applications and has become widely used in biochemistry research to induce cell rupture, extract cell constituents, and to purify, reconstitute and crystallize membrane proteins. The thermodynamic details of solubilizat...

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Detalles Bibliográficos
Autores principales: Dalgarno, Paul A., Juan-Colás, José, Hedley, Gordon J., Piñeiro, Lucas, Novo, Mercedes, Perez-Gonzalez, Cibran, Samuel, Ifor D. W., Leake, Mark C., Johnson, Steven, Al-Soufi, Wajih, Penedo, J. Carlos, Quinn, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733941/
https://www.ncbi.nlm.nih.gov/pubmed/31501469
http://dx.doi.org/10.1038/s41598-019-49210-0