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Unveiling the multi-step solubilization mechanism of sub-micron size vesicles by detergents
The solubilization of membranes by detergents is critical for many technological applications and has become widely used in biochemistry research to induce cell rupture, extract cell constituents, and to purify, reconstitute and crystallize membrane proteins. The thermodynamic details of solubilizat...
Autores principales: | Dalgarno, Paul A., Juan-Colás, José, Hedley, Gordon J., Piñeiro, Lucas, Novo, Mercedes, Perez-Gonzalez, Cibran, Samuel, Ifor D. W., Leake, Mark C., Johnson, Steven, Al-Soufi, Wajih, Penedo, J. Carlos, Quinn, Steven D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733941/ https://www.ncbi.nlm.nih.gov/pubmed/31501469 http://dx.doi.org/10.1038/s41598-019-49210-0 |
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