Yeast PAF1 complex counters the pol III accumulation and replication stress on the tRNA genes

The RNA polymerase (pol) III transcribes mostly short, house-keeping genes, which produce stable, non-coding RNAs. The tRNAs genes, highly transcribed by pol III in vivo are known replication fork barriers. One of the transcription factors, the PAF1C (RNA polymerase II associated factor 1 complex) i...

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Detalles Bibliográficos
Autores principales: Bhalla, Pratibha, Shukla, Ashutosh, Vernekar, Dipti Vinayak, Arimbasseri, Aneeshkumar Gopalakrishnan, Sandhu, Kuljeet Singh, Bhargava, Purnima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733944/
https://www.ncbi.nlm.nih.gov/pubmed/31501524
http://dx.doi.org/10.1038/s41598-019-49316-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733944/
https://www.ncbi.nlm.nih.gov/pubmed/31501524
http://dx.doi.org/10.1038/s41598-019-49316-5

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