Synthesis and Evaluations of Novel Apocynin Derivatives as Anti-Glioma Agents

Apocynin (4-hydroxy-3-methoxyacetophenone) is a natural polyphenolic compound with multiple biological activities. In the present study, a series of apocynin derivatives were designed and synthesized. The in silico ADMET prediction, blood–brain barrier (BBB) penetration assay, anti-NADPH oxidase act...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Zang, Da-Wei, Shan, Wei, Guo, An-Chen, Wu, Jian-Ping, Wang, Yong-Jun, Wang, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733959/
https://www.ncbi.nlm.nih.gov/pubmed/31551769
http://dx.doi.org/10.3389/fphar.2019.00951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733959/
https://www.ncbi.nlm.nih.gov/pubmed/31551769
http://dx.doi.org/10.3389/fphar.2019.00951

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