Iron (II) Polypyridyl Complexes as Antiglioblastoma Agents to Overcome the Blood-Brain Barrier and Inhibit Cell Proliferation by Regulating p53 and 4E-BP1 Pathways

Background and Purpose: It is urgently required to develop promising candidates to permeate across blood-brain barrier (BBB) efficiently with simultaneous disrupting vasculogenic mimicry capability of gliomas. Previously, a series of iron (II) complexes were synthesized through a modified method. He...

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Detalles Bibliográficos
Autores principales: Zhu, Huili, Dai, Chengli, He, Lizhen, Xu, Anding, Chen, Tianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733960/
https://www.ncbi.nlm.nih.gov/pubmed/31551768
http://dx.doi.org/10.3389/fphar.2019.00946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733960/
https://www.ncbi.nlm.nih.gov/pubmed/31551768
http://dx.doi.org/10.3389/fphar.2019.00946

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