α-Hispanolol Induces Apoptosis and Suppresses Migration and Invasion of Glioblastoma Cells Likely via Downregulation of MMP-2/9 Expression and p38MAPK Attenuation

α-Hispanolol (α-H) is a labdane diterpenoid that has been shown to induce apoptosis in several human cancer cells. However, the effect of α-H in human glioblastoma cells has not been described. In the present work, we have investigated the effects of α-H on apoptosis, migration, and invasion of huma...

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Detalles Bibliográficos
Autores principales: Sánchez-Martín, Vanesa, Jiménez-García, Lidia, Herranz, Sandra, Luque, Alfonso, Acebo, Paloma, Amesty, Ángel, Estévez-Braun, Ana, de las Heras, Beatriz, Hortelano, Sonsoles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733979/
https://www.ncbi.nlm.nih.gov/pubmed/31551765
http://dx.doi.org/10.3389/fphar.2019.00935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733979/
https://www.ncbi.nlm.nih.gov/pubmed/31551765
http://dx.doi.org/10.3389/fphar.2019.00935

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