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Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators

Keratinocyte differentiation requires intricately coordinated spatiotemporal expression changes that specify epidermis structure and function. This article utilizes single-cell RNA-seq data from 22,338 human foreskin keratinocytes to reconstruct the transcriptional regulation of skin development and...

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Detalles Bibliográficos
Autores principales: Finnegan, Alex, Cho, Raymond J., Luu, Alan, Harirchian, Paymann, Lee, Jerry, Cheng, Jeffrey B., Song, Jun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733986/
https://www.ncbi.nlm.nih.gov/pubmed/31552090
http://dx.doi.org/10.3389/fgene.2019.00775