Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis

Both BRCA1 and CREBBP are tumor suppressor genes that are important for hematopoiesis. We have previously shown that mouse Brca1 is essential for hematopoietic stem cell (HSC) viability. In contrast to Brca1 deficiency, which results in pancytopenia, we report here that Crebbp deficiency results in...

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Detalles Bibliográficos
Autores principales: Holmstrom, Sam R., Wijayatunge, Ranjula, McCrum, Kelly, Mgbemena, Victoria E., Ross, Theodora S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734175/
https://www.ncbi.nlm.nih.gov/pubmed/31499338
http://dx.doi.org/10.1016/j.isci.2019.08.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734175/
https://www.ncbi.nlm.nih.gov/pubmed/31499338
http://dx.doi.org/10.1016/j.isci.2019.08.031

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