Dipeptidyl Peptidase 4 Inhibition Increases Postprandial Norepinephrine via Substance P (NK1 Receptor) During RAAS Inhibition

CONTEXT: Dipeptidyl peptidase 4 (DPP4) inhibitors may increase the risk of heart failure. Decreased degradation of vasoactive peptides like substance P [also degraded by angiotensin-converting enzyme (ACE)] and Y1 agonists peptide YY (PYY 1-36) and neuropeptide Y (NPY 1-36) could contribute. OBJECTI...

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Detalles Bibliográficos
Autores principales: Wilson, Jessica R, Kerman, Scott Jafarian, Hubers, Scott A, Yu, Chang, Nian, Hui, Grouzmann, Eric, Eugster, Philippe J, Mayfield, Dustin S, Brown, Nancy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Clinical Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734191/
https://www.ncbi.nlm.nih.gov/pubmed/31528826
http://dx.doi.org/10.1210/js.2019-00185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734191/
https://www.ncbi.nlm.nih.gov/pubmed/31528826
http://dx.doi.org/10.1210/js.2019-00185

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