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Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPB(y/y) mice model
BACKGROUND: The basal transcription/repair factor TFIIH is a ten sub-unit complex essential for RNA polymerase II (RNAP2) transcription initiation and DNA repair. In both these processes TFIIH acts as a DNA helix opener, required for promoter escape of RNAP2 in transcription initiation, and to set t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734240/ https://www.ncbi.nlm.nih.gov/pubmed/31516394 http://dx.doi.org/10.1186/s12935-019-0945-4 |